Rhobust® Whey Refinery - a new cost-effective concept for optimal exploitation of whey as a raw material for value-added protein products. This concept is based on combining membrane filtration process with Upfront’s EBA platform to manufacture multiple products from crude whey on the same plant. The product list includes but not limited to the following: WPI +95 %; high purity α-lactalbumin and α-lactalbumin enriched WPI; β-lactoglobulin depleted WPI; β-lactoglobulin +95 %; Immunoglobulin enriched WPI; GMP and Lactoferrin.

• Lactoferrin and lactoperoxidase from milk or whey
• Whey Protein Isolate
• Immunoglobulin G from whey
• Separation of alpha-lactalbumin and beta-lactoglobulin from whey

Lactoferrin and lactoperoxidase from milk or whey

Upfront’s process for producing LF and LP from either milk or whey is second to none; the process can match market standard product purities at an extremely fast process flow. Thus, Rhobust® EBA enables low cost LF and LP production, and thereby lowers value-large volume applications.

Whey Protein Isolate

Get the high-quality peptide-free WPI from the cost competitive Rhobust® process. With the combination of selective adsorption and EBA, a new revolutionary method for large-scale WPI production is in place.

Immunoglobulin G from whey

This process is highly flexible in terms of purity grades. By controlling pH, you can decide for an IgG isolate product or an IgG enriched product from run to run. When applying the high flow rates from Rhobust® EBA, the process becomes economically viable. New ingredients opportunities are possible.

Separation of alpha-lactalbumin and beta-lactoglobulin from whey

By use of adsorption chromatography a palette of separation opportunities for separating alpha-lactalbumin and beta-lactoglobulin exists, enabling control of product purity. When isolating one of the molecules through binding to the adsorbent an isolate stream as well as an enrichment stream is generated. Depending on the strategy either alpha-lactalbumin or beta-lactoglobulin can be adsorbed. Alternatively, both molecules can be adsorbed from the whey stream and subsequently be eluted sequentially as protein isolates separated from each other.